crizotinib will increase amounts of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. Dose reduction may very well be necessary for coadministered medicine which might be predominantly metabolized by CYP3A.

The regulation of modafinil as being a doping agent is controversial inside the sporting world, with high-profile scenarios attracting push coverage considering the fact that various popular American athletes analyzed positive to the substance. Some athletes who used modafinil protested which the drug was not about the prohibited listing at enough time in their offenses.

nefazodone will boost the degree or outcome of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.

In the same way, it really is now mysterious regardless of whether modafinil may be transmitted to an infant through breastmilk, and equivalent cautions utilize to modafinil use by moms who're nursing [38].

modafinil will lessen the extent or outcome of iobenguane I 131 by Other (see comment). Keep away from or Use Alternate Drug. Depending on the mechanism of motion of iobenguane, prescription drugs that lower catecholamine uptake or that deplete catecholamine shops could interfere with iobenguane uptake into cells, and so, minimize iobenguane efficacy.

Observe Closely (1)voriconazole will increase the amount or influence of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

modafinil will lower the level or effect of pacritinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

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modafinil will increase the level or impact of lansoprazole by influencing hepatic enzyme CYP2C19 metabolism. Small/Significance Unknown. Net effect on pantoprazole actions mysterious resulting from opposing effects of CYP450 enzymes; check

fedratinib will raise the amount or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Alter dose of prescription drugs which might be CYP3A4 substrates as vital.

Modafinil is used to assistance Individuals who have narcolepsy, obstructive sleep apnea/hypopnea syndrome (OSAHS), or change perform slumber problem (SWSD) to stay awake during the day. Modafinil doesn't overcome these problems and can only do the job as long as you proceed to just take it.

Mitral valve prolapse (heart disease) after acquiring CNS stimulants—Use will not be suggested in clients with these conditions.

The above mentioned facts is presented for typical informational and educational needs only. Personal strategies may well change and formulary info alterations. Call the relevant plan provider for the most present info.

To keep from having pregnant, use A further method of beginning Command when you are applying this read more medicine and for just one thirty day period right after your past dose. Other kinds of start control contain condoms, diaphragms, or contraceptive foams or jellies.